Sunday, June 28, 2015

Not So Close After All...

I received my Y-67 DNA test results and have concluded that the almost-identical haplotype between Georgius Maule's family line and ours is far from enough to link the two families. The closeness of the two haplotypes (see the chart below) is misleading. A miss in this instance is as good as a mile.

User IDLast NameOriginHaplogroupTested WithMarkers ComparedGenetic Distance
WNKWHManleyTalaton, Devon, UK, United Kingdom R1b1a2a1a1b3c1 (tested) Family Tree DNA --
F4VPQMauleUnknown, England R1b1a2a1a1b3c (tested) Family Tree DNA 6737

This shows a genetic distance of 37, which is too distant to be of use in our time frame (early 1600's to now). Here is a link to a table showing genetic distance. In this instance I ran the tool on my Y-67 profile (WNKWH) and Jim Maule's Y-67 profile in Ysearch (the "public" side of Family Tree DNA).

The genetic distance (or instances where the individual markers differ) is 37. You may be related if there is a mismatch on up to 6 markers, but not above 11. Take a look at the last line in this partial graph of the link in the previous paragraph.


5-6RelatedIn this case, if you share the same surname (or a variant) with another male and you mismatch by five or  six 'points' a 61-62 for 67 match you are related.   Because of the volatility within some of the markers this result is slightly tighter then being 11/12, 23/25 or 33/37, and it's most likely that you matched 24/25, 36/37 or 37/37 on previous Y-DNA tests.  Your mismatch will most often be found within the second panel at DYS 458, 459a, 459b or within 464a-d, or at DYS 576, 570, CDYa or CDYb in the third panel of markers.   Your common ancestor is not very recent, but your mismatch is likely within the range of most well established surname lineages in Western Europe.
7Probably RelatedIn this case, if you share the same surname (or a variant) with another male and you mismatch by four 'points', a 33/37 match you are probably related.  Because of the volatility within some of the markers this is about the same as being 11/12 and it's most likely that you matched 23/25 or 24/25 on previous Y-DNA tests. If you matched exactly on previous tests you probably have a mis match at DYS 576, 570, CDYa or CDYb in the newest panel of markers.  If several or many generations have passed it is likely that these two lines are related through other family members.  That would require that each line had passed a mutation and one person would have experienced at least 2 mutations.  The only way to confirm is to test additional family lines and find where the mutations took place.  Only by testing additional family members can you find the person in between each of you...this 'in betweener' becomes essential for you to find, and without him the possibility of a match exists, but further evidence must be pursued.  If you test additional individuals you will most likely find that their DNA falls in-between the persons who are 4 apart demonstrating relatedness within this family cluster or Haplotype.
8-9Only Possibly RelatedIn this case, if you share the same surname (or a variant) with another male and you mismatch by eight or nine 'points', a 32/37 match you may be related.  It is most likely that you did not match 24/25, 25/25 or 35-37/37 in previous Y-DNA tests.   If several or many generations have passed it is possible that these two men are related through other family members. That would require that each line had experienced separate mutations and one person would have experienced at least three mutations.  The only way to confirm or deny is to test additional family lines and find where the mutation took place.  Only by testing additional family members can you find the person in between each of you...this 'in betweener' becomes essential for you to find, and without him only the possibility of a match exists, further evidence should be pursued.  If you test additional individuals you must find the person whose DNA results falls in-between the persons that are 8 or 9 apart demonstrating relatedness within this family cluster or Haplotype.
10-11Not RelatedThe 56-57 out of 67 match is too far off to be considered related, unless you can find an “in-betweener’ as for determining ‘Only Possibly Related,’ above.  It is important to determine what set of results most typifies the largest number members of the group you are 'close' to matching.  You may be 57 out of 67/ with an individual, but 61/67 with the center of the group, and your potential relatedness to him is through the center of the group.
> 11Not RelatedIn this case, for 55 out of 67 are worse, you are not related and the odds greatly favor that you have not shared a common male ancestor with this person within thousands of years.  You are probably even in different Haplogroups on the Phylogenetic tree of Homo Sapiens.

This means that it is quixotic to continue to look for a connection between George Manly and Thomas Maule, at least on the basis of DNA evidence.

But check the next posting for a possible common ancestor for the Manleys and the Maules.

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